TUMOR-ASSOCIATED MACROPHAGES PROMOTE RESISTANCE OF HEPATOCELLULAR CARCINOMA CELLS AGAINST SORAFENIB BY ACTIVATING CXCR2 SIGNALING

Tumor-associated macrophages promote resistance of hepatocellular carcinoma cells against sorafenib by activating CXCR2 signaling

Abstract Background Sorafenib (SOR) is the first line treatment for advanced hepatocellular carcinoma (HCC), but resistance develops frequently.Tumor-associated macrophages (TAMs) have been reported to affect the progression of HCC.We therefore aimed to study the role of TAMs in promoting SOR resistance.Methods Immunofluorescence staining for the M

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Prevalence of tobacco use among street children in India

Background Street children constitute one of the most vulnerable groups in India.Among marginalized children, they are at higher risk of developing COOKIE DOUGH BAR early tobacco use and thus lifelong addiction.However, literature on the tobacco use among this segment of population is scarce in India.This study estimates the prevalence of tobacco u

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